Contraindicated in:
Use Cautiously in:
CNS: SUICIDAL THOUGHTS, dizziness, drowsiness, nervousness, weakness, cognitive impairment, confusion, difficulty concentrating, hallucinations, headache, mental depression, personality disorder.
EENT: abnormal vision, ear pain, tinnitus.
Resp: dyspnea, epistaxis.
CV: chest pain, edema, hypertension, palpitations, syncope, tachycardia.
GI: abdominal pain, gingivitis, nausea, stomatitis.
GU: dysmenorrhea, dysuria, metrorrhagia, urinary incontinence.
Derm: alopecia, dry skin, rash, sweating.
Metab: weight gain, weight loss.
MS: arthralgia, neck pain.
Neuro: ataxia, tremors.
Misc: allergic reactions, chills, lymphadenopathy.
Drug-Drug:
Drug-Natural Products:
Absorption: 90% absorbed following oral administration.
Distribution: Unknown.
Protein Binding: 96%.
Metabolism/Excretion: Mostly metabolized by the liver; 2% excreted unchanged in urine.
Half-life: Without enzyme-inducing antiepileptic drugs 79 hr; with enzyme-inducing antiepileptic drugs 47 hr.
NDC Code*