tess-TOSS-te-rone sip-EYE-oh-nate 
Contraindicated in:
Use Cautiously in:
EENT: deepening of voice.
CV: MI, STROKE, VENOUS THROMBOEMBOLISM, edema.
GI: cholestatic jaundice, drug-induced hepatitis, liver function test elevation, nausea, vomiting.
GU: change in libido, erectile dysfunction, priapism, prostatic enlargement.
Endo: gynecomastia, hirsutism, oligospermia, hypercholesterolemia.
F and E: hypercalcemia, hyperkalemia, hyperphosphatemia.
Derm: male pattern baldness.
Local: pain at injection site.
Drug-Drug:
Absorption: Well absorbed from IM sites; absorbed slowly.
Distribution: Crosses the placenta.
Protein Binding: 98%.
Metabolism/Excretion: Metabolized by the liver; 90% eliminated in urine as metabolites.
Half-life: 8 days.
(androgenic effects†)
| ROUTE | ONSET | PEAK | DURATION |
|---|---|---|---|
| IM | unknown | unknown | 2–4 wk |
†Response is highly variable among individuals; may take mo.
NDC Code*