Unlabeled Use:
Contraindicated in:
Use Cautiously in:
CNS: anxiety, depression, fatigue, headache, sleep disorder.
Derm: hair thinning, pruritus, rash.
GI: abdominal/biliary pain, constipation, diarrhea, flatulence, jaundice, ↑ liver enzymes, nausea, stomatitis, vomiting.
Neuro: arthralgias, myalgia.
Resp: cough, rhinitis.
Drug-Drug:
Absorption: 90%.
Distribution: Only small quantities are found in the systemic circulation; sites of action include the liver, bile, and gut lumen.
Protein Binding: 70%.
Metabolism/Excretion: Undergoes extensive enterohepatic recycling; excreted in feces via bile.
Half-life: 100 hr.
NDC Code*