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Indications

High Alert

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: chest pain, hypertension, peripheral edema.

Derm: hot flashes, alopecia, photosensitivity, rash, sweating.

Endo: breast pain, gynecomastia, hyperglycemia.

GI: constipation, diarrhea, nausea, liver enzymes, abdominal pain, HEPATOTOXICITY, vomiting.

GU: fertility, erectile dysfunction, hematuria, incontinence, nocturia, urinary tract infections.

Hemat: anemia.

Metab: weight.

MS: pain.

Neuro: weakness, dizziness, headache, insomnia, paresthesia.

Resp: dyspnea.

Misc: flu-like syndrome, infection.

Interactions

Drug-Drug:

Availability

(Generic available)

Route/Dosage

US Brand Names

Casodex

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antineoplastics

Pharmacologic Classification: antiandrogens

Pharmacokinetics

Absorption: Well absorbed following oral administration.

Distribution: Unknown.

Protein Binding: 96%.

Metabolism/Excretion: Mostly metabolized by the liver. Excreted in the urine and feces.

Half-life: 5.8 days.

Time/Action Profile

(plasma concentrations)

ROUTEONSETPEAKDURATION
POunknown31.3 hrunknown

Patient/Family Teaching

Pronunciation

bye-ka-LOOT-a-mide

Code

NDC Code*