section name header

Indications ⬇

BEERS REMS

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

CV: hypotension, palpitations.

Derm: photosensitivity.

EENT: blurred vision, tinnitus.

GI: anorexia, dry mouth, constipation, nausea.

GU: dysuria, urinary frequency, urinary retention.

Local: pain at IM site.

Neuro: drowsiness, dizziness, headache, paradoxical excitation (↑ in children).

Resp: chest tightness, thickened bronchial secretions, wheezing.

Interactions ⬆ ⬇

Drug-Drug:

Drug-Natural Products:

Availability ⬆ ⬇

(Generic available)

Route/Dosage ⬆ ⬇

see Calculator

US Brand Names ⬆ ⬇

AllerMax, Banophen, Benadryl Dye-Free Allergy, Benadryl Allergy, Benadryl, Compoz, Compoz Nighttime Sleep Aid, Diphen AF, Diphen Cough, Genahist, 40 Winks, Hyrexin-50, Maximum Strength Nytol, Maximum Strength Sleepinal, Midol PM, Miles Nervine, Nighttime Sleep Aid, Nytol, Scot-Tussin Allergy DM, Siladril, Silphen, Sleep-Eze 3, Sleepwell 2-night, Sominex, Snooze Fast, Sominex, Tusstat, Twilite, Unisom Nighttime Sleep-Aid

Action ⬆ ⬇

Therapeutic Effects:

Classifications ⬆ ⬇

Therapeutic Classification: allergy, cold and cough remedies, antihistamines, antitussives

Pharmacokinetics ⬆ ⬇

Absorption: Well absorbed after oral or IM administration but 40–60% of an oral dose reaches systemic circulation due to first-pass metabolism.

Distribution: Widely distributed. Crosses the placenta; enters breast milk.

Metabolism/Excretion: 95% metabolized by the liver.

Half-life: 2.4–7 hr.

Canadian Brand Names ⬆ ⬇

Aller-Aide, Allerdryl, Allergy Formula, Allernix, Benylin, Calmex, Dimetane Allergy, Diphenhist, Dormex, Dormiphen, Insomnal, Nadryl

Time/Action Profile ⬆ ⬇

(antihistaminic effects)

ROUTEONSETPEAKDURATION
PO15–60 min2–4 hr4–8 hr
IM20–30 min2–4 hr4–8 hr
IVrapidunknown4–8 hr

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

dye-fen-HYE-dra-meen

Code ⬆

NDC Code*