Low-Dose Anesthesia Adjunct
- IV (Adults ): 0.5–2 mcg/kg initially, supplemental doses of 10–25 mcg may be given as needed (not to exceed 1 mcg/kg/hr when administered with nitrous oxide and oxygen).
Moderate-Dose Anesthesia Adjunct
- IV (Adults ): 2–8 mcg/kg initially, supplemental doses of 10–50 mcg may be given as needed (not to exceed 1 mcg/kg/hr when administered with nitrous oxide and oxygen).
Primary Anesthesia (with 100% Oxygen)
- IV (Adults ): 8–30 mcg/kg initially, supplemental doses of 25–50 mcg may be given as needed or a continuous infusion may be used.
- IV (Children ): Cardiovascular surgery—10–25 mcg/kg initially, followed by maintenance doses of up to 25–50 mcg; clearance in neonates is ↓ and more ↓ in neonates with cardiovascular disease, adjust dose accordingly.
Obstetrical Analgesia
- Epidural (Adults ): 10–15 mcg in combination with 10 mL of 0.0125% bupivacaine; may be repeated after 1 hour for two additional doses.
Acute Pain
- SL (Adults ): 30 mcg as needed with a minimum of 1 hr between doses (max = 12 tabs/24 hr).
Postoperative pain (unlabeled)
- Epidural (Adults ): 30–60 mcg in 10 mL of 0.9% sodium chloride; additional doses of 25 mcg may be given hourly if needed.
