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Indications ⬇

REMS

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

CV: ↑BP

Derm: STEVENS-JOHNSON SYNDROME, DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (DRESS), rash, TOXIC EPIDERMAL NECROLYSIS

GI: nausea, dry mouth

Neuro: dizziness, headache, insomnia, aggression, anxiety, delusions, hallucinations, mania, SUICIDAL IDEATION

Misc: ANAPHYLACTOID REACTIONS AND ANGIOEDEMAALLERGIC REACTIONS INCLUDING

Interactions ⬆ ⬇

Drug-drug:

Availability ⬆ ⬇

(Generic available)

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

Nuvigil

Action ⬆ ⬇

  • Produces CNS stimulation.
Therapeutic effects:
  • Improved wakefulness.

Classifications ⬆ ⬇

Therapeutic Classification: central nervous system stimulants

Pharmacokinetics ⬆ ⬇

Absorption: Readily absorbed following oral administration.

Distribution: Unknown.

Metabolism/Excretion: Mostly metabolized (partially by the CYP3A4 enzyme system; <10% excreted in urine).

Half-Life: 15 hr.

Contr. Subst. Schedule ⬆ ⬇

Schedule IV (C-IV)

Time/Action Profile ⬆ ⬇

(blood levels)

ROUTEONSETPEAKDURATION
POunknown2 hrunknown

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

ar-mo-DAF-i-nil

Code ⬆

NDC Code