Adult Dosing

Anxiety

• 50-100 mg PO qid PRN
• Max: 600 mg/day
• Alt: 50-100 mg IM q4-6 hrs PRN

Pruritus

• 25-100 mg PO tid-qid PRN

Sedation, anesthesia adjunct

• 50-100 mg PO x 1 PRN; give prior to and after anesthesia

Pediatric Dosing

Anxiety

• Child <6 yrs: 50 mg/day PO in divided doses
• Child >6 yrs: 50–100 mg/day PO in divided doses

Pruritus

• Child <6 yrs: 50 mg/day PO in divided doses
• Child >6 yrs: 50–100 mg/day PO in divided doses

Sedation, anesthesia adjunct

• 0.6 mg/kg PO x 1 PRN; give prior to and after anesthesia

[Outline]

• Adult Dosing
• Pediatric Dosing

• Anxiety
• Pruritus
• Sedation, anesthesia adjunct

• Hypersensitivity to any of the ingredients of the product
• SC, IV, or intra-arterial administration
• Pregnancy 1st trimester

• N/A

Renal Dose Adjustment (Based on CrCl)

• <50 mL/min: Reduce dose to 50%

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

• Use with caution when administering with other CNS depressants. Reduce dosage of CNS depressants
• Caution should be exercised while driving a car or operating dangerous machinery because drowsiness may occur with use of the drug
• Patients should be advised against the simultaneous use of other CNS depressant drugs, and cautioned that the effect of alcohol may be increased
• Start therapy with small dosage to avoid hepatic, renal or cardiac dysfunction
• Use with caution in elderly patients as they are more likely to have decreased renal function, care should be taken in dose selections

Cautions: Use cautiously in

• Renal impairment
• Elderly patients
• Asthma

Atarax, Vistaril interacts with :

	Aricept
	Aricept ODT
	Donepezil
	Exelon
	Galantamine
	Razadyne
	Razadyne ER
	Rivastigmine

Pregnancy Category:C

Breastfeeding: Safety unknown. Small occasional doses of hydroxyzine would not be expected to cause any adverse effects in breastfed infants. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 10 March 2011). According to manufacturer data, hydroxyzine should not be given to nursing mothers.

• CNS: Seizures, drowsiness, agitation, ataxia, dizziness, headache, weakness
• RESP: Wheezing, dyspnea
• GI: Dry mouth, bitter taste, constipation, nausea
• GU: Urinary retention
• DERM: Flushing
• MISC: Chest tightness, slurred speech

• Antianxiety, antihistaminic, sedative/hypnotics; acts as a CNS depressant at the subcortical level of the CNS; has anticholinergic, antihistaminic, and antiemetic properties, blocks histamine 1 receptors
• Well absorbed following oral administration
• Extensively metabolized by the liver
• Excreted in feces, bile
• Half-life: 3 hrs

US Trade Name(s)

• Vistaril

US Availability

hydroxyzine (generic)

• CAPS: 25, 50, 100 mg
• SYRUP: 10 mg/5 mL
• TABS: 10, 25, 50 mg

Vistaril

• CAPS: 25, 50 mg
• SUSP: 25 mg/5 mL (Discontinued)

Canadian Trade Name(s)

• Atarax

Canadian Availability

hydroxyzine (generic)

• CAPS: 10, 25, 50 mg
• SYRUP: 10 mg/5 mL

Atarax

• SYRUP: 2mg/mL

UK Trade Name(s)

• Atarax
• Ucerax

UK Availability

Atarax

• TABS: 10, 25 mg

Ucerax

• SYRUP: 10 mg/5 mL
• TABS: 25 mg

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Allergy & Immunology

Antihistamines

ENT

Antihistamines

Psychiatric

Anxiolytics/Sedatives/Hypnotics

Miscellaneous Agents

Neurologic

Anxiolytics/Sedatives/Hypnotics

Miscellaneous Agents

Pricing data from www.DrugStore.com in U.S.A.

• Vistaril 25 MG CAPS [Bottle] (PFIZER U.S.)
  30 mg = $60.99
  90 mg = $159.99
• Vistaril 50 MG CAPS [Bottle] (PFIZER U.S.)
  30 mg = $70.61
  90 mg = $189.59

Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

• Atarax 10 MG Oral Tablet (Roerig)
• Atarax 100 MG Oral Tablet (Roerig)
• Atarax 25 MG Oral Tablet (Roerig)
• Atarax 50 MG Oral Tablet (Roerig)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Actavis Totowa LLC)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Caraco Pharmaceutical Laboratories, Ltd.)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Glenmark Generics Inc., USA)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Heritage Pharmaceuticals Inc.)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Mutual Pharmaceutical Company, Inc. )
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Mylan Pharmaceuticals Inc.)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (N/A)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (NCS HealthCare of KY, Inc dba Vangard Labs)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Northstar RxLLC)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Physicians Total Care, Inc.)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Piramal Healthcare Limited)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Qualitest Pharmaceuticals)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (UDL Laboratories, Inc.)
• Hydroxyzine Hydrochloride 10 MG Oral Tablet (Watson Laboratories, Inc.)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Actavis Totowa LLC)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Caraco Pharmaceutical Laboratories, Ltd.)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Glenmark Generics Inc., USA)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Heritage Pharmaceuticals Inc.)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Mutual Pharmaceutical Company, Inc. )
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Mylan Pharmaceuticals Inc.)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (N/A)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (NCS HealthCare of KY, Inc dba Vangard Labs)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Northstar RxLLC)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Physicians Total Care, Inc.)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Piramal Healthcare Limited)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Qualitest Pharmaceuticals)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (UDL Laboratories, Inc.)
• Hydroxyzine Hydrochloride 50 MG Oral Tablet (Watson Laboratories, Inc.)
• Hydroxyzine hydrochloride 100 MG (hydroxyzine pamoate 170.4 MG) Oral Capsule (BARR LABORATORIES, INC.)
• Hydroxyzine hydrochloride 100 MG (hydroxyzine pamoate 170.4 MG) Oral Capsule (State of Florida DOH Central Pharmacy)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Capsule (BARR LABORATORIES, INC.)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Capsule (NCS HealthCare of KY, Inc dba Vangard Labs)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Capsule (Sandoz Inc.)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Capsule (State of Florida DOH Central Pharmacy)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Capsule (Watson Laboratories, Inc.)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Capsule (Watson Labs)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Actavis Totowa LLC)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Caraco Pharmaceutical Laboratories, Ltd.)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Glenmark Generics Inc., USA)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Heritage Pharmaceuticals Inc.)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Mutual Pharmaceutical Company, Inc. )
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Mylan Pharmaceuticals Inc.)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (N/A)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (NCS HealthCare of KY, Inc dba Vangard Labs)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Northstar RxLLC)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Physicians Total Care, Inc.)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Piramal Healthcare Limited)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Qualitest Pharmaceuticals)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (UDL Laboratories, Inc.)
• Hydroxyzine hydrochloride 25 MG (hydroxyzine pamoate 42.6 MG) Oral Tablet (Watson Laboratories, Inc.)
• Hydroxyzine hydrochloride 50 MG (hydroxyzine pamoate 85.2 MG) Oral Capsule (BARR LABORATORIES, INC.)
• Hydroxyzine hydrochloride 50 MG (hydroxyzine pamoate 85.2 MG) Oral Capsule (NCS HealthCare of KY, Inc dba Vangard Labs)
• Hydroxyzine hydrochloride 50 MG (hydroxyzine pamoate 85.2 MG) Oral Capsule (Sandoz Inc.)
• Hydroxyzine hydrochloride 50 MG (hydroxyzine pamoate 85.2 MG) Oral Capsule (State of Florida DOH Central Pharmacy)
• Hydroxyzine hydrochloride 50 MG (hydroxyzine pamoate 85.2 MG) Oral Capsule (Watson Laboratories, Inc.)
• Vistaril 100 MG Oral Capsule (Pfizer Laboratories Div Pfizer Inc)
• Vistaril 25 MG Oral Capsule (Pfizer Laboratories Div Pfizer Inc)
• Vistaril 50 MG Oral Capsule (Pfizer Laboratories Div Pfizer Inc)