section name header

Use and Dosing

Adult Dosingnavigator.gif

Depression

Pediatric Dosingnavigator.gif

Nocturnal enuresis


[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment

Hepatic Dose Adjustment

Warnings/Precautions

See Supplemental Patient Information

Cautions: Use cautiously in

Supplemental Patient Information

Interactions

Tofranil, Tofranil-PM interacts with :

significance_3.gifAbiraterone
significance_3.gifAbstral
significance_3.gifActiq
significance_3.gifAcular
significance_3.gifAcular LS
significance_3.gifAcuvail
significance_3.gifAdvil
significance_3.gifAdvil liqui-gels
significance_3.gifAdvil migraine liqui-gels
significance_3.gifAleve
significance_3.gifAlfenta
significance_3.gifAlfentanil
significance_3.gifAlka-Seltzer Plus Allergy
significance_3.gifAmiodarone
significance_3.gifAnaprox
significance_3.gifAnaprox DS
significance_3.gifAnsaid
significance_3.gifAplenzin
significance_3.gifAricept
significance_3.gifAricept ODT
significance_3.gifAtazanavir
significance_2.gifAzilect
significance_3.gifBarbiturates
significance_3.gifBenadryl
significance_3.gifBenadryl Allergy
significance_3.gifBenadryl extra strength itch stopping
significance_3.gifBosentan
significance_3.gifBrisdelle
significance_3.gifBupropion
significance_3.gifCambia
significance_3.gifCarbamazepine
significance_3.gifCarbatrol
significance_3.gifCataflam
significance_2.gifCatapres
significance_2.gifCatapres-TTS-1
significance_2.gifCatapres-TTS-2
significance_2.gifCatapres-TTS-3
significance_3.gifChildren's advil
significance_3.gifChildren's advil flavored
significance_3.gifChildren's Benadryl Allergy
significance_3.gifChildren's elixsure
significance_3.gifChildren's ibuprofen
significance_3.gifChildren's motrin
significance_3.gifCimetidine
significance_3.gifCinacalcet
significance_3.gifClinoril
significance_3.gifClobazam
significance_2.gifClonidine
significance_3.gifConivaptan
significance_3.gifConzip
significance_3.gifCordarone
significance_3.gifCymbalta
significance_3.gifDabrafenib
significance_3.gifDaypro
significance_3.gifDecadron
significance_3.gifDemerol
significance_3.gifDexamethasone
significance_3.gifDiclofenac
significance_3.gifDiflunisal
significance_3.gifDilantin
significance_3.gifDilantin Infatabs
significance_3.gifDilantin-125
significance_3.gifDiphenhydramine
significance_3.gifDolobid
significance_3.gifDolophine
significance_3.gifDonepezil
significance_3.gifDuloxetine
significance_2.gifDuraclon
significance_3.gifDuragesic
significance_3.gifEC-Naprosyn
significance_3.gifEfavirenz
significance_2.gifEldepryl
significance_2.gifEmsam
significance_3.gifEpitol
significance_3.gifEquetro
significance_3.gifEtodolac
significance_3.gifExelon
significance_3.gifFeldene
significance_3.gifFenoprofen
significance_3.gifFentanyl
significance_3.gifFentora
significance_3.gifFlector
significance_3.gifFluoxetine
significance_3.gifFlurbiprofen
significance_3.gifFluvoxamine
significance_3.gifForfivo XL
significance_1.gifFurazolidone
significance_1.gifFuroxone
significance_3.gifGalantamine
significance_2.gifGuanabenz
significance_2.gifGuanfacine
significance_3.gifHaldol
significance_3.gifHaloperidol
significance_3.gifIbu-tab
significance_3.gifIbu-tab 200
significance_3.gifIbuprofen
significance_3.gifIbuprohm
significance_3.gifIndocin
significance_3.gifIndomethacin
significance_3.gifInfants' advil
significance_3.gifInfants' motrin
significance_2.gifIntuniv
significance_1.gifIsocarboxazid
significance_3.gifJunior strength advil
significance_3.gifJunior strength ibuprofen
significance_3.gifJunior strength motrin
significance_2.gifKapvay
significance_3.gifKetoprofen
significance_3.gifKetorolac
significance_3.gifLamisil
significance_3.gifLamisil AT
significance_3.gifLazanda
significance_2.gifLinezolid
significance_3.gifLodine
significance_3.gifLumacaftor
significance_3.gifLuvox
significance_3.gifLuvox CR
significance_1.gifMarplan
significance_3.gifMaxidex
significance_3.gifMeclofenamate
significance_3.gifMefenamic acid
significance_3.gifMellaril
significance_3.gifMeloxicam
significance_3.gifMeperidine
significance_3.gifMethadone
significance_3.gifMethadose
significance_1.gifMethblue
significance_1.gifMethylene Blue
significance_3.gifMidol Extended Relief
significance_3.gifMidol liquid gels
significance_3.gifMirabegron
significance_3.gifMobic
significance_3.gifMotrin
significance_3.gifMotrin IB
significance_3.gifMotrin migraine pain
significance_3.gifMycobutin
significance_3.gifMyrbetriq
significance_3.gifMysoline
significance_3.gifNabumetone
significance_3.gifNalfon
significance_3.gifNaprelan
significance_3.gifNaprosyn
significance_3.gifNaproxen
significance_1.gifNardil
significance_3.gifNefazodone
significance_3.gifNevirapine
significance_3.gifNexcede
significance_3.gifNexterone
significance_3.gifNorvir
significance_3.gifNucynta
significance_3.gifNucynta ER
significance_3.gifNytol
significance_3.gifOcufen
significance_3.gifOnfi
significance_3.gifOnsolis
significance_3.gifOrkambi
significance_3.gifOrudis
significance_3.gifOxaprozin
significance_3.gifOxcarbazepine
significance_3.gifOxtellar XR
significance_3.gifOzudrex
significance_3.gifPacerone
significance_3.gifPamprin All Day
significance_1.gifParnate
significance_3.gifParoxetine
significance_3.gifPaxil
significance_3.gifPaxil CR
significance_3.gifPediaCare Children's Allergy
significance_3.gifPediaCare Children's Pain Reliever/ Fever Reducer IB
significance_3.gifPediaCare Infants' Pain Reliever/ Fever Reducer IB
significance_3.gifPediatric advil
significance_3.gifPennsaid
significance_3.gifPexeva
significance_1.gifPhenelzine
significance_3.gifPhenytek
significance_3.gifPhenytoin
significance_3.gifPiroxicam
significance_3.gifPonstel
significance_3.gifPriftin
significance_3.gifPrimidone
significance_3.gifProfen
significance_3.gifPropafenone
significance_3.gifProzac
significance_3.gifProzac Weekly
significance_3.gifQuinidex
significance_3.gifQuinidine
significance_3.gifRanexa
significance_3.gifRanolazine
significance_2.gifRasagiline
significance_3.gifRazadyne
significance_3.gifRazadyne ER
significance_3.gifRelafen
significance_3.gifReyataz
significance_3.gifRifabutin
significance_3.gifRifadin
significance_3.gifRifampin
significance_3.gifRifapentine
significance_3.gifRimactane
significance_3.gifRitonavir
significance_3.gifRivastigmine
significance_3.gifRybix ODT
significance_3.gifRythmol
significance_3.gifRythmol SR
significance_3.gifRyzolt
significance_2.gifSafinamide
significance_3.gifSarafem
significance_2.gifSelegiline
significance_3.gifSelfemra
significance_3.gifSensipar
significance_3.gifSimply Sleep
significance_3.gifSolaraze
significance_3.gifSominex Extra Strength
significance_3.gifSominex Original
significance_3.gifSprix
significance_3.gifSt. John's Wort
significance_3.gifSublimaze
significance_3.gifSubsys
significance_3.gifSulindac
significance_3.gifSustiva
significance_3.gifTab-profen
significance_3.gifTafinlar
significance_3.gifTagamet
significance_3.gifTagamet HB
significance_3.gifTapentadol
significance_3.gifTegretol
significance_3.gifTegretol XR
significance_2.gifTenex
significance_3.gifTerbinafine
significance_3.gifTeril
significance_3.gifThiazide Diuretics
significance_3.gifThioridazine
significance_3.gifTivorbex
significance_3.gifTolectin
significance_3.gifTolmetin
significance_3.gifToradol
significance_3.gifTracleer
significance_3.gifTramadol
significance_3.gifTranquil
significance_1.gifTranylcypromine
significance_3.gifTrileptal
significance_3.gifUltram
significance_3.gifUltram ER
significance_3.gifUnisom SleepGels
significance_3.gifUnisom SleepMelts
significance_1.gifUrolene Blue
significance_3.gifVaprisol
significance_3.gifVicks ZzzQuil
significance_3.gifViramune
significance_3.gifViramune XR
significance_3.gifVoltaren
significance_3.gifVoltaren Gel
significance_3.gifVoltaren ophthalmic
significance_3.gifVoltaren-XR
significance_3.gifWellbutrin
significance_3.gifWellbutrin SR
significance_3.gifWellbutrin XL
significance_3.gifWestadone
significance_2.gifWytensin
significance_2.gifXadago
significance_2.gifZelapar
significance_3.gifZipsor
significance_3.gifZorvolex
significance_3.gifZyban
significance_3.gifZytiga
significance_2.gifZyvox

Pregnancy/Breast Feeding

Pregnancy Category:D

Breastfeeding: Low levels of imipramine and its metabolite are detected in the serum of breastfed infants. Use of imipramine during breastfeeding is unexpected to cause any adverse effects in breastfed infants, especially if the infant is >2 months. Prefer other agents when large doses are required or while nursing a newborn or preterm infant. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 10 March 2011). According to manufacturer's data woman taking a drug should not nurse as possibility exists that the drug may be excreted in breast milk and be harmful to the child.

Adverse Reactions

Clinical Pharmacology

Brands and Availability

flag_usa32.png

US Trade Name(s)

US Availability

imipramine (generic)

Tofranil

Tofranil-PM

flag_canada32.png

Canadian Trade Name(s)

Canadian Availability

imipramine (generic)

Impril

Pramine

UK Availability

imipramine (generic)

flag_australia32.png

Australian Trade Name(s)

Australian Availability

Tofranil, Tolerade


[Outline]

flag_usa32.pngflag_canada32.pngflag_uk32.pngflag_australia32.png

Classification

Psychiatric

Antidepressants
Tricyclic Antidepressants

Neurologic

Antidepressants
Tricyclic Antidepressants

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill