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Use and Dosing

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Epilepsy adjunct

Lamotrigine, Lamictal

Lamictal XR

Epilepsy - Conversion to lamotrigine monotherapy

gteq.gif16 yrs

Bipolar disorder maintenance; escalation regimen

Lamotrigine, Lamictal

Bipolar disorder; dosage adjustments following discontinuation of psychotropic medicines

Lamotrigine, Lamictal

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Epilepsy adjunct

Lamotrigine, Lamictal

Lamotrigine, Lamictal

Lamictal XR


[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment (Based on CrCl)

Hepatic Dose Adjustment

Discontinuation of Dosing

Warnings/Precautions

See Supplemental Patient Information

Cautions: Use cautiously in

Supplemental Patient Information

Interactions

Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR interacts with :

significance_3.gifBarbiturates
significance_3.gifCarbamazepine
significance_3.gifCarbatrol
significance_3.gifDabrafenib
significance_3.gifDepakene
significance_3.gifDilantin
significance_3.gifDilantin Infatabs
significance_3.gifDilantin-125
significance_3.gifEfavirenz
significance_3.gifEpitol
significance_3.gifEquetro
significance_3.gifMycobutin
significance_3.gifMysoline
significance_3.gifNevirapine
significance_3.gifOral Contraceptives
significance_3.gifPhenytek
significance_3.gifPhenytoin
significance_3.gifPriftin
significance_3.gifPrimidone
significance_3.gifRifabutin
significance_3.gifRifadin
significance_3.gifRifampin
significance_3.gifRifapentine
significance_3.gifRimactane
significance_3.gifSt. John's wort
significance_3.gifStavzor
significance_3.gifSustiva
significance_3.gifTafinlar
significance_3.gifTegretol
significance_3.gifTegretol XR
significance_3.gifTeril
significance_3.gifValproic Acid
significance_3.gifViramune
significance_3.gifViramune XR

Pregnancy/Breast Feeding

Pregnancy Category:C

Breastfeeding: Unsafe. Lamotrigine is excreted in breastmilk. Infant plasma concentration averages 30-35% of maternal serum levels. It can cause potentially fatal skin reactions in the breastfed infants. If breastfeeding is continued during therapy, monitor infants for side effects such as rash, drowsiness or poor sucking, including measurement of serum levels to rule out toxicity. Discontinue breastfeeding if rash occurs. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 6 April 2011). Manufacturer advises caution. Discontinue breastfeeding if lamotrigine toxicity is evident in infants

Adverse Reactions

Clinical Pharmacology

Brands and Availability

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US Trade Name(s)

US Availability

lamotrigine (generic)

Lamictal

Lamictal XR

Lamictal CD

Lamictal ODT

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Canadian Trade Name(s)

Canadian Availability

lamotrigine (generic)

Lamictal

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UK Trade Name(s)

UK Availability

lamotrigine (generic)

Lamictal

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Australian Trade Name(s)

Australian Availability

lamotrigine (generic)

Lamictal, Seaze

Elmendos

Lamidus

Lamitrin

Lamogine

Lamotrust


[Outline]

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Classification

Neurologic

Anticonvulsants
Triazine Anticonvulsants

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill