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List of Diseases and Injuries

Symptoms and signs involving cognition, perception, emotional state and behavior (R40-R46)


Excludes 2: symptoms and signs constituting part of a pattern of mental disorder (F01-F99)

R40Somnolence, stupor and coma
Excludes 1: neonatal coma (P91.5)
› somnolence, stupor and coma in diabetes (E08-E13)
› somnolence, stupor and coma in hepatic failure (K72.-)
› somnolence, stupor and coma in hypoglycemia (nondiabetic) (E15)

R40.0Somnolence
› Drowsiness

Excludes 1: coma (R40.2-)

R40.1Stupor
› Catatonic stupor
› Semicoma

Excludes 1: catatonic schizophrenia (F20.2)
› coma (R40.2-)
› depressive stupor (F31-F33)
› dissociative stupor (F44.2)
› manic stupor (F30.2)

R40.2Coma
Code First: any associated:
› fracture of skull (S02.-)
› intracranial injury (S06.-)


One code from each subcategory, R40.21-R40.23, is required to complete the coma scale

R40.20Unspecified coma
› Coma NOS
› Unconsciousness NOS

R40.21Coma scale, eyes open
The following appropriate 7th character is to be added to subcategory R40.21-:

7th Character: 0 :: unspecified time
› 1 :: in the field [EMT or ambulance]
› 2 :: at arrival to emergency department
› 3 :: at hospital admission
› 4 :: 24 hours or more after hospital admission

R40.211Coma scale, eyes open, never
› Coma scale eye opening score of 1

R40.212Coma scale, eyes open, to pain
› Coma scale eye opening score of 2

R40.213Coma scale, eyes open, to sound
› Coma scale eye opening score of 3

R40.214Coma scale, eyes open, spontaneous
› Coma scale eye opening score of 4

R40.22Coma scale, best verbal response
The following appropriate 7th character is to be added to subcategory R40.22-:

7th Character: 0 :: unspecified time
› 1 :: in the field [EMT or ambulance]
› 2 :: at arrival to emergency department
› 3 :: at hospital admission
› 4 :: 24 hours or more after hospital admission

R40.221Coma scale, best verbal response, none
› Coma scale verbal score of 1

R40.222Coma scale, best verbal response, incomprehensible words
› Coma scale verbal score of 2
› Incomprehensible sounds (2-5 years of age)
› Moans/grunts to pain; restless (2 years old)

R40.223Coma scale, best verbal response, inappropriate words
› Coma scale verbal score of 3
› Inappropriate crying or screaming ( 2 years of age)
› Screaming (2-5 years of age)

R40.224Coma scale, best verbal response, confused conversation
› Coma scale verbal score of 4
› Inappropriate words (2-5 years of age)
› Irritable cries ( 2 years of age)

R40.225Coma scale, best verbal response, oriented
› Coma scale verbal score of 5
› Cooing or babbling or crying appropriately ( 2 years of age)
› Uses appropriate words (2- 5 years of age)

R40.23Coma scale, best motor response
The following appropriate 7th character is to be added to subcategory R40.23-:

7th Character: 0 :: unspecified time
› 1 :: in the field [EMT or ambulance]
› 2 :: at arrival to emergency department
› 3 :: at hospital admission
› 4 :: 24 hours or more after hospital admission

R40.231Coma scale, best motor response, none
› Coma scale motor score of 1

R40.232Coma scale, best motor response, extension
› Abnormal extensor posturing to pain or noxious stimuli ( 2 years of age)
› Coma scale motor score of 2
› Extensor posturing to pain or noxious stimuli (2-5 years of age)

R40.233Coma scale, best motor response, abnormal flexion
› Abnormal flexure posturing to pain or noxious stimuli (2-5 years of age)
› Coma scale motor score of 3
› Flexion/decorticate posturing ( 2 years of age)

R40.234Coma scale, best motor response, flexion withdrawal
› Coma scale motor score of 4
› Withdraws from pain or noxious stimuli (2-5 years of age)

R40.235Coma scale, best motor response, localizes pain
› Coma scale motor score of 5
› Localizes pain (2-5 years of age)
› Withdraws to touch ( 2 years of age)

R40.236Coma scale, best motor response, obeys commands
› Coma scale motor score of 6
› Normal or spontaneous movement ( 2 years of age)
› Obeys commands (2-5 years of age)

R40.24Glasgow coma scale, total score


Assign a code from subcategory R40.24, when only the total coma score is documented


The following appropriate 7th character is to be added to subcategory R40.24-:

7th Character: 0 :: unspecified time
› 1 :: in the field [EMT or ambulance]
› 2 :: at arrival to emergency department
› 3 :: at hospital admission
› 4 :: 24 hours or more after hospital admission

R40.241Glasgow coma scale score 13-15

R40.242Glasgow coma scale score 9-12

R40.243Glasgow coma scale score 3-8

R40.244Other coma, without documented Glasgow coma scale score, or with partial score reported

R40.2ANontraumatic coma due to underlying condition
› Secondary coma

Code First: underlying condition

R40.3Persistent vegetative state

R40.4Transient alteration of awareness

R41Other symptoms and signs involving cognitive functions and awareness
Excludes 1: dissociative [conversion] disorders (F44.-)
› mild cognitive impairment of uncertain or unknown etiology (G31.84)

R41.0Disorientation, unspecified
› Confusion NOS
› Delirium NOS

R41.1Anterograde amnesia

R41.2Retrograde amnesia

R41.3Other amnesia
› Amnesia NOS
› Memory loss NOS

Excludes 1: amnestic disorder due to known physiologic condition (F04)
› amnestic syndrome due to psychoactive substance use (F10-F19 with 5th character .6)
› mild memory disturbance due to known physiological condition (F06.8)
› transient global amnesia (G45.4)

R41.4Neurologic neglect syndrome
› Asomatognosia
› Hemi-akinesia
› Hemi-inattention
› Hemispatial neglect
› Left-sided neglect
› Sensory neglect
› Visuospatial neglect

Excludes 1: visuospatial deficit (R41.842)

R41.8Other symptoms and signs involving cognitive functions and awareness

R41.81Age-related cognitive decline
› Senility NOS

R41.82Altered mental status, unspecified
› Change in mental status NOS

Excludes 1: altered level of consciousness (R40.-)
› altered mental status due to known condition - code to condition
› delirium NOS (R41.0)

R41.83Borderline intellectual functioning
› IQ level 71 to 84

Excludes 1: intellectual disabilities (F70-F79)

R41.84Other specified cognitive deficit
Excludes 1: cognitive deficits as sequelae of cerebrovascular disease (I69.01-, I69.11-, I69.21-, I69.31-, I69.81-, I69.91-)

R41.840Attention and concentration deficit
Excludes 1: attention-deficit hyperactivity disorders (F90.-)

R41.841Cognitive communication deficit

R41.842Visuospatial deficit

R41.843Psychomotor deficit

R41.844Frontal lobe and executive function deficit

R41.89Other symptoms and signs involving cognitive functions and awareness
› Anosognosia

R41.9Unspecified symptoms and signs involving cognitive functions and awareness
› Unspecified neurocognitive disorder

R42Dizziness and giddiness
› Light-headedness
› Vertigo NOS

Excludes 1: vertiginous syndromes (H81.-)
› vertigo from infrasound (T75.23)

R43Disturbances of smell and taste

R43.0Anosmia

R43.1Parosmia

R43.2Parageusia

R43.8Other disturbances of smell and taste
› Mixed disturbance of smell and taste

R43.9Unspecified disturbances of smell and taste

R44Other symptoms and signs involving general sensations and perceptions
Excludes 1: alcoholic hallucinations (F10.151, F10.251, F10.951)
› hallucinations in drug psychosis (F11-F19 with fifth to sixth characters 51)
› hallucinations in mood disorders with psychotic symptoms (F30.2, F31.5, F32.3, F33.3)
› hallucinations in schizophrenia, schizotypal and delusional disorders (F20-F29)

Excludes 2: disturbances of skin sensation (R20.-)

R44.0Auditory hallucinations

R44.1Visual hallucinations

R44.2Other hallucinations

R44.3Hallucinations, unspecified

R44.8Other symptoms and signs involving general sensations and perceptions

R44.9Unspecified symptoms and signs involving general sensations and perceptions

R45Symptoms and signs involving emotional state

R45.0Nervousness
› Nervous tension

R45.1Restlessness and agitation

R45.2Unhappiness

R45.3Demoralization and apathy
Excludes 1: anhedonia (R45.84)

R45.4Irritability and anger

R45.5Hostility

R45.6Violent behavior

R45.7State of emotional shock and stress, unspecified

R45.8Other symptoms and signs involving emotional state

R45.81Low self-esteem

R45.82Worries

R45.83Excessive crying of child, adolescent or adult
Excludes 1: excessive crying of infant (baby) R68.11

R45.84Anhedonia

R45.85Homicidal and suicidal ideations
Excludes 1: suicide attempt (T14.91)

R45.850Homicidal ideations

R45.851Suicidal ideations

R45.86Emotional lability

R45.87Impulsiveness

R45.88Nonsuicidal self-harm
› Nonsuicidal self-injury
› Nonsuicidal self-mutilation
› Self-inflicted injury without suicidal intent

Code Also: injury, if known

R45.89Other symptoms and signs involving emotional state
› Flat affect
› Loneliness

R46Symptoms and signs involving appearance and behavior
Excludes 1: appearance and behavior in schizophrenia, schizotypal and delusional disorders (F20-F29)
› mental and behavioral disorders (F01-F99)

R46.0Very low level of personal hygiene

R46.1Bizarre personal appearance

R46.2Strange and inexplicable behavior

R46.3Overactivity

R46.4Slowness and poor responsiveness
Excludes 1: stupor (R40.1)

R46.5Suspiciousness and marked evasiveness

R46.6Undue concern and preoccupation with stressful events

R46.7Verbosity and circumstantial detail obscuring reason for contact

R46.8Other symptoms and signs involving appearance and behavior

R46.81Obsessive-compulsive behavior
Excludes 1: obsessive-compulsive disorder (F42.-)

R46.89Other symptoms and signs involving appearance and behavior