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Symptoms ⬇

Pain, redness, and swelling over the lacrimal sac in the innermost aspect of the lower eyelid. Tearing, discharge, fever, or chills may also be present. Symptoms may be recurrent.

Signs ⬆ ⬇

(See Figure 6.9.1.)

Critical

Erythematous, tender, tense swelling over the nasal aspect of the lower eyelid and extending around the periorbital area. Mucoid or purulent discharge can be expressed from the punctum when pressure is applied over the lacrimal sac.

NOTE:

Swelling in dacryocystitis is below the medial canthal tendon. Suspect lacrimal sac tumor (rare) if the mass is above the medial canthal tendon.

Other

Fistula formation from the skin below the medial canthal tendon. A lacrimal sac cyst or mucocele can occur in chronic cases. Progression to a lacrimal sac abscess, and rarely, orbital or facial cellulitis may occur.

6-9.1 Dacryocystitis.

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Differential Diagnosis ⬆ ⬇

  • Facial cellulitis involving the medial canthal area: No discharge from punctum with pressure over the lacrimal sac. The lacrimal drainage system is patent on irrigation. See 6.10, PRESEPTAL CELLULITIS.
  • Dacryocystocele: Mild enlargement of noninflamed lacrimal sac in an infant. Present at birth, but may not be detected until later. Caused by nasolacrimal duct obstruction or entrapment of mucus or amniotic fluid in the lacrimal sac and usually unilateral. If bilateral, assess breathing to rule out nasal obstruction. Conservative therapy with digital massage, antibiotic ointment, and warm compresses is usually sufficient for nonobstructive cases.
  • Acute ethmoid sinusitis: Pain, tenderness, nasal obstruction, and erythema over the nasal bone, just medial to the inner canthus. Patients may be febrile. Imaging is diagnostic.
  • Frontal sinus mucocele/mucopyocele: Swelling typically occurs well above the medial canthal tendon. Proptosis, downward and lateral displacement of the globe, and external ophthalmoplegia are often present. Imaging is diagnostic.

Etiology ⬆ ⬇

  • Almost always related to nasolacrimal duct obstruction.
  • Uncommon causes include lacrimal sac diverticula, dacryoliths, nasal or sinus surgery, trauma, and rarely lacrimal sac tumors.
  • Gram-positive bacteria are the most common pathogens; gram-negative and atypical organisms are seen more commonly in diabetics, immunocompromised, and nursing home patients.

Work Up ⬆ ⬇

Workup
  1. History: Distinguish reflex tearing from epiphora. Previous episodes? Concomitant ear, nose, or throat infection? Underlying sinus disease? Prior trauma or surgery?
  2. External examination: Apply gentle pressure to the lacrimal sac in the nasal corner of the lower eyelid with a cotton-tipped swab in an attempt to express discharge from the punctum. Perform bilaterally to uncover subtle contralateral dacryocystitis.
  3. Evaluation for orbital signs: Assess pupillary response, extraocular motility, globe position for proptosis, and other evidence of potentially concurrent orbital cellulitis.
  4. Obtain Gram stain and blood agar culture (consider chocolate agar culture in children given the higher incidence of Haemophilus influenzae) of any discharge expressed from the punctum.
  5. Consider a CT scan of the orbits and paranasal sinuses in atypical cases, severe cases, and those that do not respond to appropriate antibiotics.
NOTE:

Do not attempt to probe or irrigate the lacrimal system during the acute infection. If a large abscess is present superficially, incision and drainage will alleviate pain and hasten healing.

Treatment ⬆ ⬇

  1. Systemic antibiotics in the following regimen: Children older than 5 years and <40 kg:
    • Afebrile, systemically well, mild case, and reliable parent: Amoxicillin/clavulanate: 25 to 45 mg/kg/d p.o. in two divided doses for children, with a maximum daily dose of 90 mg/kg/d.
    • Alternative treatment: Cefpodoxime: 10 mg/kg/d p.o. in two divided doses for children, with a maximum daily dose of 400 mg.
    • Febrile, acutely ill, moderate-to-severe case, or unreliable parent: Hospitalize and treat with cefuroxime, 50 to 100 mg/kg/d i.v. in three divided doses in consultation with an infectious disease specialist.
      Adults:
    • Afebrile, systemically well, mild case, and reliable patient: Cephalexin 500 mg p.o. q6h or amoxicillin/clavulanate 500/125 mg t.i.d. or 875/125 mg p.o. b.i.d.
    • If exposure to methicillin-resistant Staphylococcus aureus (MRSA) is suspected, then start one to two tablets double-strength trimethoprim–sulfamethoxazole 160/800 mg p.o. q12h for adults. Alternatively, start clindamycin 300 mg p.o. t.i.d. In addition to covering MRSA, this antibiotic also gives good coverage for anaerobes, streptococci, and methicillin-sensitive S. aureus.
    • Febrile, acutely ill, or unreliable: Hospitalize and treat with cefazolin 1 g i.v. q8h. See 7.3.1, ORBITAL CELLULITIS.
    • The antibiotic regimen is adjusted according to the clinical response and culture/sensitivity test results. I.V. antibiotics can be changed to comparable p.o. antibiotics depending on the rate of improvement, but systemic antibiotic therapy should be continued for at least a full 10- to 14-day course.
  2. Topical antibiotic drops (e.g., trimethoprim/polymyxin B q.i.d.) may be used in addition to systemic therapy. Topical therapy alone is not adequate.
  3. Apply warm compresses and gentle massage to the inner canthal region for 5 to 10 minutes q.i.d.
  4. Administer pain medication (e.g., acetaminophen with or without codeine) p.r.n.
  5. Consider incision and drainage of a pointing abscess.
  6. Once infection has resolved, evaluate patency of the nasolacrimal duct system with probing and irrigation. If an obstruction is present, consider surgical correction (e.g., dacryocystorhinostomy with silicone intubation). In cases of recurrent or chronic dacryocystitis, surgical correction is recommended.

Follow Up ⬆

Daily, until improvement is confirmed. If outpatient condition worsens, hospitalization and i.v. antibiotics are recommended. Upon resolution of acute infection, probing and irrigation are required at the follow up to assess the patency of the nasolacrimal drainage system.