section name header
References
Parkinson's Disease - Related Resources
Cochrane reviews
Early
bromocriptine
/levodopa combination therapy
as
a strategy to prevent
or
delay the onset of
motor complications
in the treatment of Parkinson's disease may not be better than levodopa therapy alone
Bromocriptine/Levodopa Combined Vs. Levodopa Alone for Early Parkinson's Disease
.
Speech
and language therapy may increase the loudness of
patients
' voices in Parkinson's disease
Speech and Language Therapy for Dysarthria in Parkinson's Disease
.
Physiotherapy
appears to be effective in Parkinson's disease for a short term. Based on indirect comparisons there appears to be no differences between the different physiotherapy interventions used
Physiotherapy for Patients with Parkinson's Disease
.
There is not enough evidence to assess the effectiveness of
occupational therapy
in Parkinson's disease
Occupational Therapy for Patients with Parkinson's Disease
.
MAO-B inhibitors may have weaker symptomatic effects than levodopa and
dopamine agonists
in early Parkinson's disease. They may reduce the rate of motor fluctuations compared with initial levodopa therapy and may have fewer significant
adverse effects
than the older agonists
Monoamine Oxidase B Inhibitors Versus other Dopaminergic Agents in Early Parkinson's Disease
.
Parkinson's disease patients with impaired
gait
probably benefit from treadmill
training
Treadmill Training for Patients with Parkinson's Disease
.
In
Parkinson
´s disease add-on therapy for levodopa may reduce off-
time
and required levodopa
dose
as well as improve overall
disability
scores on the expense of
dyskinesia
and other side-effects. Dopamine agonists may provide more effective symptomatic
control
than
catechol-O-methyl transferase inhibitors
(COMTI) and monoamine oxidase type B inhibitors (MAOBI) therapy
Adjuvant Treatment to Levodopa Therapy in Parkinson´s Disease Patients with Motor Complications
.
Other evidence summaries
Clozapine
appears to be effective for the treatment of
drug
-induced psychosis in Parkinson's disease
Treating Dopamimetic Psychosis in Parkinson's Disease
.
Other
Internet
resources
Young
adult
-onset Parkinsonism. Orphanet ORPHA2828
http://www.orpha.net/consor/cgi-bin/Disease_Search.php?data_id=932
Progressive supranuclear palsy. Orphanet ORPHA683
http://www.orpha.net/consor/cgi-bin/Disease_Search.php?data_id=846
Multiple system
atrophy
. Orphanet ORPHA102
http://www.orpha.net/consor/cgi-bin/Disease_Search.php?data_id=8744
Corticobasal degeneration. Orphanet ORPHA278
http://www.orpha.net/consor/cgi-bin/Disease_Search.php?data_id=8735
Familial
Parkinson's disease
dementia
. Orphanet ORPHA33540
http://www.orpha.net/consor/cgi-bin/Disease_Search.php?data_id=10325
Literature
Lewitt PA. Levodopa for the treatment of Parkinson's disease. N Engl J Med 2008
Dec
4;359(23):2468-76.
[PubMed]
Primary/Secondary Keywords
Related resources