Contraindicated in:
Use Cautiously in:
CNS: depression, dizziness, emotional lability, headache, nervousness.
CV: THROMBOEMBOLIC EVENTS, hypertension.
GI: hepatic adenomas.
GU: dysmenorrhea, irregular/unpredictable menses, ↑ risk of ectopic pregnancy, ovarian cysts.
Derm: acne.
Endo: breast pain, leukorrhea.
Local: implant site reactions.
Metab: weight gain.
MS: back pain.
Drug-Drug:
Drug-Natural Products:
Absorption: Reliably, constantly and slowly absorbed (100% bioavailable).
Distribution: Crosses the placenta and enters breast milk.
Metabolism/Excretion: Mostly metabolized by the liver.
Half-life: 25 hr.