Adult Dosing
Seasonal allergic rhinitis, perennial allergic rhinitis, chronic urticaria
- 5-10 mg PO daily
- Max: 10 mg/day
Pediatric Dosing
Seasonal allergic rhinitis, perennial allergic rhinitis, chronic urticaria
Child 6 month-2 yrs
- 2.5 mg (1/2 tsp) PO daily. In children >12 month, upto 5 mg (1/2 tsp bid) may be given
Child 2-5 yrs
- Start 2.5 (1/2 tsp) - 5 mg (1tsp) PO daily. 5 mg dose may be given divided bid
- Max: 5 mg/day
Child 6-11 yrs
- 5-10 mg (1-2 tsp) PO daily
[Outline]
Renal Dose Adjustment (Based on CrCl)
Adults
- <30 mL/min: Max: 5 mg/day
- Hemodialysis: No supplement
Child
- <6 yrs: Avoid use
- Child 6-11 yrs
- <30 mL/min: Max: 2.5 mg/day
- Hemodialysis: No supplement
- Child >12 yrs
- <30 mL/min: Max: 5 mg/day
- Hemodialysis: No supplement
Hepatic Dose Adjustment
Adults
- Hepatic impairment: Max: 5 mg/day
Child
- <6 yrs: Avoid use
- Child 6-11 yrs: Max: 2.5 mg/day
- Child >12 yrs: Max: 5 mg/day
- Cetirizine may cause drowsiness and/or sedation. Occurence of somnolence has also been reported. This effect may be enhanced with alcohol, sedatives, and other CNS depressants. Advise patients not to engage in activities requiring mental alertness and motor coordination, such as driving a car or operating machinery
- Assess patient for allergy symptoms (eg, hives, itching, nasal congestion, rhinitis etc) before starting therapy, and periodically throughout therapy
- Safety and efficacy is not established in children younger than 6 months of age
Cautions: Use cautiously in
- Hepatic impairment
- Renal impairment
- Concomitant CNS depressants
- Substance abuse
Pregnancy Category:B
Breastfeeding: Small occasional doses of cetirizine are acceptable during breastfeeding. Larger doses or more prolonged use may cause drowsiness and or interfere with lactation, particularly when used in combination with a sympathomimetic or before lactation is well established. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 11 May 2010). Manufacturer does not recommend use of Zyrtec in nursing mothers.
US Trade Name(s)
- Children's Zyrtec Allergy
- Zyrtec
- Zyrtec allergy
- Zyrtec hives relief
- Children's Zyrtec Hives Relief
- Cetirizine Hydrochloride Allergy
- Cetirizine Hydrochloride Hives Relief
- PediaCare Children's 24 Hour Allergy
- Cetirizine Hydrochloride Hives
US Availability
cetrizine (generic)
- TABS: 5, 10 mg
- CHEW TABS: 5, 10 mg
- CAPS: 5, 10 mg
- SYRUP: 5 mg/5 mL
Children's Zyrtec Allergy
- CHEW TABS: 5, 10 mg
- SYRUP: 5 mg/5 mL
Zyrtec
Zyrtec allergy, Zyrtec hives relief
Children's Zyrtec Hives Relief
- CHEW TABS: 5, 10 mg
- SYRUP: 5 mg/5 mL
Cetirizine Hydrochloride Allergy
- OTC TABS: 5, 10 mg
- OTC CHEW TABS: 5, 10 mg
- OTC CAPS: 5, 10 mg
Cetirizine Hydrochloride Hives Relief
PediaCare Children's 24 Hour Allergy
Cetirizine Hydrochloride Hives
Canadian Trade Name(s)
- Aller Relief
- Allergy Relief
- Extra strength Allergy Relief
- Reactine
Canadian Availability
cetrizine (generic)
Aller Relief, Allergy Relief, Extra strength Allergy Relief
Reactine
- TABS: 5, 10, 20 mg
- CHEW TABS: 5, 10 mg
- STRUP: 5 mg/5 mL
UK Trade Name(s)
- Benadryl Allergy Oral Syrup
- Benadryl for Children Allergy Solution
- Benadryl One a Day
- Benadryl One a Day relief
- Boots Hayfever and allergy Relief
- Piriteze
- Pollenshield Hayfever
- Pollenshield Hayfever Relief
- Zirtek allergy
- Zirtek allergy relief
- Zirtek allergy relief for children
UK Availability
cetrizine (generic)
- TABS: 10 mg
- SYRUP: 5 mg/5 mL (10, 200 mL)
Benadryl Allergy Oral Syrup
- SYRUP: 1 mg/mL (75, 100, 200 mL)
Benadryl for children allergy solution
Benadryl one a day
Benadryl One a Day relief
Boots Hayfever and allergy Relief
Piriteze
- TABS: 10 mg
- SYRUP: 1 mg/mL (70 mL)
Pollenshield Hayfever, Pollenshield Hayfever Relief
Zirtek Allergy, Zirtek Allergy Relief
Zirtek Allergy Relief for Children
- SYRUP: 1 mg/mL (70, 75, 100, 150, 200 mL)
Australian Trade Name(s)
- Alzene
- ZepAllergy
- Zilarex
- Zodac
- Zyrtec
Australian Availability
Alzene, ZepAllergy, Zilarex, Zodac
Zyrtec
- TABS: 10 mg
- ODT: 10 mg
- SOLN: 1 mg/mL (75, 200 mL)
- SOLN: 10 mg/mL (20 mL)
[Outline]
