section name header

Use and Dosing

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Transplant rejection prophylaxis (modified formulations)

Transplant rejection prophylaxis (Non modified formulations)

Rheumatoid arthritis, severe (modified formulations)

Psoriasis (modified formulations)

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Pediatric Use


[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment

Hepatic Dose Adjustment

Warnings/Precautions

Cautions: Use Cautiously in

Interactions

Gengraf, Neoral, Sandimmune interacts with :

significance_2.gif8-MOP
significance_3.gifA-methapred
significance_3.gifAbilify
significance_3.gifAbilify discmelt
significance_3.gifAbilify Maintena
significance_3.gifAbiraterone
significance_3.gifAbstral
significance_3.gifActiq
significance_3.gifActos
significance_3.gifAdalat CC
significance_3.gifAdcetris
significance_3.gifAdcirca
significance_3.gifAddyi
significance_3.gifAdriamycin
significance_3.gifAfeditab CR
significance_3.gifAgenerase
significance_2.gifAkne-mycin
significance_3.gifAlfenta
significance_3.gifAlfentanil
significance_2.gifAlfuzosin
significance_2.gifAlmotriptan
significance_3.gifAlprazolam
significance_2.gifAltropev
significance_3.gifAmbien
significance_3.gifAmiodarone
significance_3.gifAmlodipine
significance_3.gifAmprenavir
significance_3.gifAnastrozole
significance_2.gifAndrogens
significance_3.gifApixaban
significance_3.gifAprepitant
significance_2.gifAralen
significance_3.gifArimidex
significance_3.gifAripiprazole
significance_3.gifAristocort
significance_3.gifAromasin
significance_3.gifAsmanex
significance_3.gifAsmanex Twisthaler
significance_3.gifAtazanavir
significance_2.gifAtorvastatin
significance_3.gifAvanafil
significance_2.gifAxert
significance_3.gifAxitinib
significance_2.gifAzaSite
significance_2.gifAzithromycin
significance_3.gifAzmacort
significance_2.gifBarbiturates
significance_3.gifBaypress
significance_3.gifBedaquiline
significance_3.gifBepridil
significance_2.gifBerberine
significance_3.gifBetrixaban (Bevyxxa)
significance_3.gifBexarotene
significance_2.gifBiaxin
significance_2.gifBiaxin XL
significance_3.gifBoceprevir
significance_3.gifBortezomib
significance_2.gifBosentan
significance_3.gifBosulif
significance_3.gifBosutinib
significance_3.gifBrentuximab
significance_3.gifBrexpiprazole
significance_3.gifBudesonide
significance_3.gifBuSpar
significance_3.gifBuspirone
significance_3.gifCabazitaxel
significance_3.gifCabozantinib
significance_2.gifCafergot
significance_3.gifCalan
significance_3.gifCalan SR
significance_3.gifCamptosar
significance_3.gifCaprelsa
significance_3.gifCarbamazepine
significance_3.gifCarbatrol
significance_3.gifCardene
significance_3.gifCardene SR
significance_3.gifCardizem
significance_3.gifCardizem CD
significance_3.gifCardizem LA
significance_3.gifCartia XT
significance_3.gifCentrex
significance_2.gifCerdelga
significance_3.gifCeritinib
significance_2.gifCetraxal
significance_2.gifChloroquine
significance_3.gifCialis
significance_2.gifCiloxan
significance_2.gifCipro
significance_2.gifCipro IV
significance_2.gifCipro XR
significance_2.gifCiprofloxacin
significance_2.gifClarithromycin
significance_3.gifClonazepam
significance_3.gifClorazepate
significance_2.gifClotrimazole
significance_3.gifClozapine
significance_3.gifClozaril
significance_3.gifCobicistat
significance_3.gifCobimetinib
significance_2.gifColchicine
significance_2.gifColcrys
significance_3.gifCometriq
significance_3.gifConivaptan
significance_2.gifContraceptives, Oral
significance_3.gifCordarone
significance_2.gifCorlanor
significance_3.gifCortisone
significance_3.gifCortone
significance_3.gifCotellic
significance_3.gifCovera-HS
significance_2.gifCrestor
significance_3.gifCrixivan
significance_3.gifCrizotinib
significance_3.gifCutivate
significance_3.gifCyclophosphamide
significance_3.gifCytoxan
significance_2.gifD.H.E. 45
significance_3.gifDabigatran
significance_3.gifDabrafenib
significance_2.gifDaclatasvir
significance_2.gifDaklinza
significance_3.gifDalmane
significance_2.gifDanazol
significance_2.gifDanocrine
significance_3.gifDarunavir
significance_3.gifDasatinib
significance_3.gifDecadron
significance_3.gifDelavirdine
significance_3.gifDepo-Medrol
significance_3.gifDexamethasone
significance_3.gifDiastat
significance_3.gifDiastat AcuDial
significance_3.gifDiazepam
significance_2.gifDiflucan
significance_2.gifDihydroergotamine
significance_3.gifDilacor XR
significance_2.gifDilantin
significance_2.gifDilantin Infatabs
significance_2.gifDilantin-125
significance_3.gifDilt-CD
significance_3.gifDiltiazem
significance_3.gifDiltzac
significance_3.gifDisopyramide
significance_3.gifDocetaxel
significance_3.gifDolophine
significance_3.gifDoral
significance_3.gifDoxorubicin
significance_3.gifDronedarone
significance_3.gifDuragesic
significance_3.gifDynacirc
significance_3.gifDynacirc CR
significance_2.gifE-Mycin
significance_2.gifE.E.S.
significance_3.gifEdoxaban
significance_3.gifEdurant
significance_2.gifEfavirenz
significance_2.gifEletriptan
significance_2.gifEliglustat
significance_3.gifEliquis
significance_3.gifElocon
significance_3.gifEmend
significance_3.gifEntocort
significance_3.gifEntocort EC
significance_3.gifEnzalutamide
significance_3.gifEpitol
significance_2.gifEplerenone
significance_3.gifEquetro
significance_2.gifErgomar
significance_2.gifErgotamine
significance_3.gifErlotinib
significance_2.gifEry-Tab
significance_2.gifEryc
significance_2.gifErygel
significance_2.gifEryped
significance_2.gifErythra-Derm
significance_2.gifErythro-statin
significance_2.gifErythrocin
significance_2.gifErythromycin
significance_3.gifEstazolam
significance_3.gifEszopiclone
significance_3.gifEtoposide
significance_2.gifEtravirine
significance_3.gifExemestane
significance_2.gifExtina
significance_3.gifFanapt
significance_3.gifFareston
significance_3.gifFarydak
significance_3.gifFazaclo ODT
significance_3.gifFelodipine
significance_3.gifFemara
significance_3.gifFentanyl
significance_3.gifFentora
significance_3.gifFlibanserin
significance_3.gifFlo-Pred
significance_3.gifFlonase
significance_3.gifFlovent
significance_3.gifFlovent Diskus
significance_3.gifFlovent HFA
significance_2.gifFluconazole
significance_3.gifFlurazepam
significance_3.gifFluticasone
significance_2.gifFluvoxamine
significance_2.gifFungicure Intensive Pump Spray
significance_2.gifFungicure Manicure & Pedicure
significance_2.gifFungicure Pump Spray
significance_3.gifGefitinib
significance_3.gifGen-Xene
significance_3.gifGeodon
significance_3.gifGleevec
significance_2.gifGoldenseal
significance_3.gifGrapefruit
significance_2.gifGyne-Lotrimin
significance_2.gifGyne-Lotrimin 3
significance_2.gifGyne-Lotrimin 3 combination pack
significance_2.gifGyne-Lotrimin combination pack
significance_3.gifHalazepam
significance_3.gifHalcion
significance_3.gifIbrutinib
significance_3.gifIdelalisib
significance_3.gifIfex
significance_3.gifIfosfamide
significance_3.gifIloperidone
significance_3.gifImatinib
significance_3.gifImbruvica
significance_3.gifIncivek
significance_3.gifIndinavir
significance_3.gifInlyta
significance_2.gifInspra
significance_2.gifIntelence
significance_3.gifInvirase
significance_3.gifIressa
significance_3.gifIrinotecan
significance_3.gifIsoptin
significance_3.gifIsoptin SR
significance_3.gifIsradipine
significance_2.gifItraconazole
significance_2.gifIvabradine
significance_3.gifIxabepilone
significance_3.gifIxazomib
significance_3.gifIxempra
significance_3.gifJakafi
significance_3.gifJanumet
significance_3.gifJanuvia
significance_3.gifJevtana
significance_3.gifJuxtapid
significance_2.gifKaletra
significance_3.gifKenalog
significance_3.gifKenalog-10
significance_3.gifKenalog-40
significance_2.gifKetek
significance_2.gifKetoconazole
significance_3.gifKlonopin
significance_3.gifKorlym
significance_3.gifLanoxicaps
significance_3.gifLanoxin
significance_3.gifLanoxin pediatric
significance_3.gifLapatinib
significance_3.gifLatuda
significance_3.gifLazanda
significance_3.gifLetrozole
significance_3.gifLevitra
significance_2.gifLipitor
significance_2.gifLivalo
significance_3.gifLomitapide
significance_2.gifLopinavir
significance_2.gifLotrimin AF
significance_2.gifLovastatin
significance_2.gifLumacaftor
significance_3.gifLunesta
significance_3.gifLurasidone
significance_2.gifLuvox
significance_2.gifLuvox CR
significance_3.gifMaraviroc
significance_3.gifMaxidex
significance_3.gifMedrol
significance_3.gifMethadone
significance_3.gifMethadose
significance_2.gifMethoxsalen
significance_3.gifMethylprednisolone
significance_2.gifMethysergide
significance_2.gifMevacor
significance_3.gifMidazolam
significance_3.gifMifepristone
significance_2.gifMigranal
significance_3.gifMillipred
significance_3.gifMometasone
significance_3.gifMultaq
significance_2.gifMycelex
significance_2.gifMycelex 7
significance_2.gifMycelex 7 combination pack
significance_2.gifMycobutin
significance_2.gifMysoline
significance_3.gifNasacort allergy 24 Hour
significance_3.gifNasacort AQ
significance_3.gifNasonex
significance_3.gifNateglinide
significance_2.gifNavelbine
significance_2.gifNefazodone
significance_3.gifNelfinavir
significance_2.gifNevirapine
significance_3.gifNexavar
significance_3.gifNexterone
significance_3.gifNicardipine
significance_3.gifNifediac CC
significance_3.gifNifedical XL
significance_3.gifNifedipine
significance_3.gifNilotinib
significance_3.gifNimodipine
significance_3.gifNimotop
significance_3.gifNinlaro
significance_3.gifNiravam
significance_3.gifNisoldipine
significance_3.gifNitrendipine
significance_2.gifNizoral
significance_2.gifNizoral A-D Shampoo
significance_2.gifNizoral Shampoo
significance_3.gifNorpace
significance_3.gifNorpace CR
significance_3.gifNorvasc
significance_3.gifNorvir
significance_2.gifNoxafil
significance_3.gifNymalize
significance_3.gifOdomzo
significance_3.gifOlanzapine
significance_3.gifOmnipred
significance_2.gifOncovin
significance_3.gifOnglyza
significance_2.gifOnmel
significance_3.gifOnsolis
significance_1.gifOrap
significance_3.gifOrapred
significance_3.gifOrapred ODT
significance_3.gifOrasone
significance_2.gifOrkambi
significance_3.gifOsimertinib
significance_2.gifOxcarbazepine
significance_3.gifOxecta
significance_2.gifOxsoralen
significance_2.gifOxsoralen-Ultra
significance_2.gifOxtellar XR
significance_3.gifOxycodone
significance_3.gifOxycontin
significance_3.gifOxyFast
significance_3.gifOzudrex
significance_3.gifPacerone
significance_3.gifPaclitaxel
significance_3.gifPanobinostat
significance_3.gifPaxipam
significance_3.gifPazopanib
significance_2.gifPCE
significance_2.gifPediamycin
significance_3.gifPercocet
significance_2.gifPhenytek
significance_2.gifPhenytoin
significance_1.gifPimozide
significance_3.gifPioglitazone
significance_2.gifPitavastatin
significance_3.gifPlendil
significance_2.gifPosaconazole
significance_3.gifPradaxa
significance_3.gifPrandin
significance_2.gifPravachol
significance_2.gifPravastatin
significance_3.gifPrazepam
significance_3.gifPred forte
significance_3.gifPred mild
significance_3.gifPrednisolone
significance_3.gifPrednisone
significance_3.gifPrelone
significance_3.gifPrezista
significance_2.gifPriftin
significance_2.gifPrimidone
significance_3.gifProcardia
significance_3.gifProcardia XL
significance_2.gifProquin XR
significance_3.gifProSom
significance_3.gifPulmicort flexhaler
significance_3.gifPulmicort respules
significance_3.gifPulmicort turbuhaler
significance_3.gifQuazepam
significance_3.gifQuetiapine
significance_3.gifQuinidex
significance_3.gifQuinidine
significance_2.gifQuinupristin
significance_2.gifRanexa
significance_2.gifRanolazine
significance_3.gifRayos
significance_3.gifRegorafenib
significance_2.gifRelpax
significance_3.gifRepaglinide
significance_3.gifRescriptor
significance_3.gifRevatio
significance_3.gifRexulti
significance_3.gifReyataz
significance_3.gifRhinocort
significance_2.gifRifabutin
significance_2.gifRifadin
significance_2.gifRifampin
significance_2.gifRifapentine
significance_3.gifRilpivirine
significance_2.gifRimactane
significance_3.gifRisperdal
significance_3.gifRisperdal Consta
significance_3.gifRisperdal M-Tab
significance_3.gifRisperidone
significance_3.gifRitonavir
significance_3.gifRivaroxaban
significance_2.gifRosuvastatin
significance_3.gifRoxicodone
significance_3.gifRuxolitinib
significance_2.gifSansert
significance_3.gifSaquinavir
significance_3.gifSavaysa
significance_3.gifSaxagliptin
significance_3.gifSelzentry
significance_3.gifSeroquel
significance_3.gifSeroquel XR
significance_3.gifSildenafil
significance_2.gifSimvastatin
significance_3.gifSirturo
significance_3.gifSitagliptin
significance_3.gifSolu-Medrol
significance_3.gifSonata
significance_3.gifSonidegib
significance_3.gifSorafenib
significance_2.gifSporanox
significance_3.gifSprycel
significance_2.gifSt. John's wort
significance_3.gifStarlix
significance_3.gifStaxyn
significance_3.gifStendra
significance_3.gifSterapred
significance_3.gifSterapred DS
significance_3.gifStivarga
significance_3.gifStribild
significance_3.gifSublimaze
significance_3.gifSubsys
significance_3.gifSufenta
significance_3.gifSufentanil
significance_3.gifSular
significance_3.gifSunitinib
significance_2.gifSustiva
significance_3.gifSutent
significance_2.gifSynercid
significance_3.gifTadalafil
significance_3.gifTafinlar
significance_3.gifTagrisso
significance_2.gifTAO
significance_3.gifTarceva
significance_3.gifTargretin
significance_3.gifTasigna
significance_3.gifTaxol
significance_3.gifTaxotere
significance_3.gifTaztia XT
significance_3.gifTegretol
significance_3.gifTegretol XR
significance_3.gifTelaprevir
significance_2.gifTelithromycin
significance_3.gifTeniposide
significance_3.gifTeril
significance_3.gifTiazac
significance_3.gifTofacitinib
significance_3.gifToremifene
significance_3.gifTrabectedin
significance_2.gifTracleer
significance_3.gifTranxene
significance_3.gifTriacet
significance_3.gifTriamcinolone
significance_3.gifTriazolam
significance_3.gifTriderm
significance_3.gifTriesence
significance_2.gifTrileptal
significance_2.gifTrivagizole 3
significance_2.gifTroleandomycin
significance_3.gifTykerb
significance_3.gifUceris
significance_2.gifUroxatral
significance_2.gifUvadex
significance_3.gifValium
significance_3.gifVandetanib
significance_3.gifVaprisol
significance_3.gifVardenafil
significance_3.gifVascor
significance_2.gifVelban
significance_3.gifVelcade
significance_3.gifVemurafenib
significance_3.gifVenclexta
significance_3.gifVenetoclax
significance_3.gifVepesid
significance_3.gifVeralan
significance_3.gifVeramyst
significance_3.gifVerapamil
significance_3.gifVerelan PM
significance_3.gifVeripred 20
significance_3.gifVersacloz
significance_3.gifVersed
significance_2.gifVfend
significance_3.gifViagra
significance_3.gifVictrelis
significance_2.gifVinblastine
significance_2.gifVincristine
significance_2.gifVinorelbine
significance_3.gifViracept
significance_2.gifViramune
significance_2.gifViramune XR
significance_2.gifVoriconazole
significance_3.gifVotrient
significance_3.gifVumon
significance_3.gifWestadone
significance_3.gifXalkori
significance_3.gifXanax
significance_3.gifXanax XR
significance_3.gifXarelto
significance_3.gifXeljanz
significance_2.gifXolegel
significance_3.gifXtandi
significance_3.gifYondelis
significance_2.gifZ-max
significance_3.gifZaleplon
significance_3.gifZelboraf
significance_3.gifZiprasidone
significance_2.gifZithromax
significance_2.gifZocor
significance_3.gifZolpidem
significance_3.gifZydelig
significance_3.gifZykadia
significance_3.gifZyprexa
significance_3.gifZyprexa Relprevv
significance_3.gifZyprexa Zydis
significance_3.gifZytiga

Pregnancy/Breast Feeding

Pregnancy Category:C

Breastfeeding: Safety unknown. Cyclosporine concentration in milk is variable. Limited information indicates that cyclosporine produces low levels in breast milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. With typical maternal cyclosporine blood levels, a completely breastfed infant would usually receive about 2% of the maternal weight-adjusted dosage or pediatric transplantation maintenance dosage. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACTlast accessed 2 November 2009). Manufacturer advises a decision to be made whether to discontinue nursing or to discontinue the drug after considering maternal importance of therapy. Ethanol is present in breast milk, and may be orally absorbed by a nursing infant.

Adverse Reactions

Clinical Pharmacology

Brands and Availability

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US Trade Name(s)

US Availability

cyclosporine (generic; modified)

cyclosporine (generic; non modified)

Gengraf, Neoral (Modified)

Sandimune (non modified)

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Canadian Trade Name(s)

Canadian Availability

cyclosporine (generic)

Neoral

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UK Trade Name(s)

UK Availability

Deximune

Neoral

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Australian Trade Name(s)

Australian Availability

Cicloral

Neoral

Sandimmun


[Outline]

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Classification

Allergy & Immunology

Immunosuppressants

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill