Contraindicated in:
Use Cautiously in:
When used in combination with other antiretrovirals
CV: PR interval prolongation, heart block
Derm: DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (DRESS), ERYTHEMA MULTIFORME, rash, STEVENS-JOHNSON SYNDROME
Endo: Graves' disease, hyperglycemia
GI: nausea, ↑liver enzymes, abdominal pain, autoimmune hepatitis, cholelithiasis, diarrhea, HEPATOTOXICITY, hyperbilirubinemia, jaundice, vomiting
GU: interstitial nephritis, nephrolithiasis
MS: myalgia, polymyositis
Neuro: depression, dizziness, Guillain-Barré syndrome, headache, insomnia
Misc: ANGIOEDEMA, fever, immune reconstitution syndrome
Drug-drug:
Drug-Natural Products:
Renal Impairment
Hepatic Impairment
Lab Test Considerations: