Glaucoma caused by a fibrovascular membrane overgrowing the anterior chamber angle structures. Initially, despite an open appearance on gonioscopy, the angle may be blocked by the membrane. The fibrovascular membrane eventually contracts, causing PAS formation and secondary angle closure glaucoma. Rarely, it may have NV of the angle without NV of the iris (NVI) at the pupillary margin. Ischemia-driven vascular endothelial growth factor (VEGF) release from a variety of causes results in the formation of the fibrovascular membrane.
(See Figures 9.14.1 and 9.14.2.)
Critical
Other
Mild anterior chamber cell and flare, conjunctival injection, corneal edema with acute IOP increase, hyphema, eversion of pupillary margin allowing visualization of iris pigment epithelium (ectropion uveae), optic nerve cupping, and visual field loss.
NOTE: |
Miotics (e.g., pilocarpine) are contraindicated because of their effects on the bloodaqueous barrier. Epinephrine compounds (e.g., dipivefrin) are usually ineffective. |