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References
Memory Complaints, Mild Cognitive Impairment and Dementia - Related Resources
Cochrane reviews
Statins
appear not to be effective in preventing
Alzheimer's
disease
or
dementia given in late life to individuals
at
risk
of vascular disease
Prevention of Dementia by Statins
.
Donepezil
appears not to be effective in preventing the development of Alzheimer's disease during 3 years'
treatment
in
patients
with mild cognitive impairment (
MCI
,
MMSE
>
23) and its use is associated with a significant
incidence
of side effects. Donepezil appears to be associated with a modest and clinically questionable
benefit
on a 13-item the ADAS-Cog
scale
but not on
other
measures of
cognitive function
Donepezil for Mild Cognitive Impairment
.
In
healthy
elderly
people cognitive interventions might possibly
lead
to performance improvements, although the evidence is insufficient
Cognition-Based Interventions for Healthy Older People and People with Mild Cognitive Impairment
.
Blood pressure
lowering appears to not prevent the development of dementia or cognitive impairment in hypertensive patients with no apparent prior cerebrovascular disease
Blood Pressure Lowering for Prevention of Dementia in Patients Without Prior Cerebrovascular Disease
.
Aerobic physical activities which improve
cardiorespiratory fitness
appear to be beneficial for cognitive function in healthy older
adults
without known cognitive impairment
Aerobic Exercise to Improve Cognitive Function in Older People Without Known Cognitive Impairment
.
Cholinesterase inhibitors
do probably not have an effect on
progression
to dementia or cognitive
test
scores in mild cognitive impairment but may increase the risk of particularly gastrointestinal
adverse events
Cholinesterase Inhibitors for Mild Cognitive Impairment
.
Literature
Clinical practice reviews
Iliffe S, Pealing L. Subjective memory problems. BMJ 2010
Mar
19;340():c1425.
[PubMed]
Primary/Secondary Keywords
Related resources