Polycystic Ovary Syndrome (PCOS) - Related Resources

Cochrane reviews

Metformin treatment before and during assisted reproductive techniques (IVF or ICSI) seems not to be effective in increasing live birth rate in infertile women with polycystic ovary syndrome, however it may reduce the risk of ovarian hyperstimulation syndrome Metformin Treatment Before and during Ivf or Icsi in Women with Polycystic Ovary Syndrome.
There may be a non-significant trend towards better pregnancy rates with the addition of a GnRH analogue to gonadotrophin stimulation in patients with PCOS, but further studies are needed Gonadotropin Therapy for Ovulation Induction in Polycystic Ovary Syndrome.

Nestler JE. Metformin for the treatment of the polycystic ovary syndrome. N Engl J Med 2008 Jan 3;358(1):47-54. [PubMed]
Glueck CJ, Papanna R, Wang P, Goldenberg N, Sieve-Smith L. Incidence and treatment of metabolic syndrome in newly referred women with confirmed polycystic ovarian syndrome. Metabolism 2003 Jul;52(7):908-15. [PubMed]

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