DDx ⬇
- Chronic alcoholism (alcoholic pseudo-Cushing's syndrome)
- Diabetes mellitus
- Depression (may have hypercortisolism)
- Osteoporosis due to other causes
- Obesity due to other causes
- Primary hyperaldosteronism
- Anorexia nervosa (high urine free cortisol)
- Striae distensae ("stress marks")
- Lipodystrophy from antiretrovirals
Related DDx ⬆ ⬇
Etiology ⬆
- Exogenous corticosteroids
- Cushing's disease (pituitary adenoma)
- Adrenal adenoma, carcinoma, or hyperplasia
- Ectopic adrenocorticotropic hormone (ACTH), eg, small-cell lung cancer