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Indications

REMS

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: peripheral vasculopathy, SUDDEN DEATH, tachycardia.

EENT: visual disturbances.

GI: abdominal pain, anorexia, nausea.

GU: libido changes, priapism.

Metab: growth suppression, weight loss (may occur with prolonged use).

MS: RHABDOMYOLYSIS.

Neuro: twitching, behavioral disturbances, hallucinations, insomnia, mania, nervousness, thought disorder.

Misc: fever, HYPERSENSITIVITY REACTIONS (INCLUDING ANAPHYLAXIS AND ANGIOEDEMA).

Interactions

Drug-Drug:

Availability

(Generic available)

Route/Dosage

Tablets

Extended-Release Capsules

US Brand Names

Focalin, Focalin XR

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: central nervous system stimulants

Pharmacokinetics

Absorption: Readily absorbed following oral administration.

Distribution: Unknown.

Metabolism/Excretion: Mostly metabolized by the liver; inactive metabolites are renally excreted.

Half-life: 2.2 hr.

Contr. Subst. Schedule

Schedule II (C-II)

Time/Action Profile

(improvement in symptoms)

ROUTEONSETPEAKDURATION
PO7 days1 mounknown

Patient/Family Teaching

Pronunciation

dex-meth-ill-FEN-i-date audio

Code

NDC Code*