Contraindicated in:
Use Cautiously in:
CV: HF, arrhythmias, dyspnea, edema, heart block, hypotension.
EENT: dry eyes, blurred vision, dry throat.
Endo: hypoglycemia.
GI: constipation, dry mouth, abdominal pain, flatulence, nausea.
GU: urinary hesitancy, urinary retention.
Neuro: fatigue, dizziness, headache.
Misc: impaired temperature regulation.
Drug-Drug:
Drug-Natural Products:
Renal Impairment
Absorption: Well absorbed from the GI tract.
Distribution: Widely distributed to tissues.
Metabolism/Excretion: Metabolized by the liver; 10% excreted unchanged in the feces, 50% excreted unchanged by the kidneys.
Half-life: 818 hr (↑ in hepatic or renal impairment).
(antiarrhythmic effects)
ROUTE | ONSET | PEAK | DURATION |
---|---|---|---|
PO | 0.53.5 hr | 2.5 hr | 1.58.5 hr |
PO-CR | 0.53.5 hr | 4.9 hr | 12 hr |
NDC Code*