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Indications

BEERS REMS

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: peripheral edema.

Derm: photosensitivity.

EENT: abnormal vision, altered sense of smell, ear pain, epistaxis, hearing sensitivity, ocular pain.

GI: abdominal pain, anorexia, colitis, dyspepsia, nausea.

GU: dysmenorrhea.

Neuro: abnormal thinking, amnesia, anxiety, behavior changes, COMPLEX SLEEP BEHAVIORS (INCLUDING SLEEP DRIVING, SLEEP WALKING, OR ENGAGING IN OTHER ACTIVITIES WHILE SLEEPING), depersonalization, dizziness, drowsiness, hallucinations, headache, hyperesthesia, impaired memory (briefly following dose), impaired psychomotor function (briefly following dose), malaise, nightmares, paresthesia, tremor, vertigo, weakness.

Misc: fever.

Interactions

Drug-Drug:

Drug-Natural Products:

Drug-Food:

Availability

(Generic available)

Route/Dosage

Hepatic Impairment

US Brand Names

Sonata

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: sedative/hypnotics

Pharmacokinetics

Absorption: Rapidly absorbed following oral administration.

Distribution: Well distributed to tissues.

Metabolism/Excretion: Extensively metabolized in the liver (mostly by aldehyde oxidase and some by the CYP3A4 isoenzyme).

Half-life: 1 hr.

Contr. Subst. Schedule

Schedule IV (C-IV)

Time/Action Profile

ROUTEONSETPEAKDURATION
POwithin minunknown3–4 hr

Patient/Family Teaching

Pronunciation

za-LEP-lon audio

Code

NDC Code*