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Information

Correlates with age, serum bilirubin, serum albumin, prothrombin time, edema.

Treatment: Primary BILIARY Cirrhosis

Ursodeoxycholic acid 13-15 mg/kg per day has been shown to improve the biochemical and histologic features of disease. Response is greatest when given early. Cholestyramine 4 g PO with meals for pruritus; in refractory cases consider rifampin, naltrexone, plasmapheresis. Calcium, vitamin D, and bisphosphonates are given for osteoporosis. Liver transplantation for end-stage disease.

Outline

Section 11. Gastroenterology