Partial hepatectomy in normal, noncirrhotic livers is associated with mortality rates of 1% to 2% (improved surgical and anesthetic techniques).
Bleeding remains a major complication, and the hepatic veins are a significant source of blood loss. Techniques to maintain CVP at normal or even low (<5 cm H2O) levels have been suggested to limit blood loss (controversial).
Vasopressors have a direct effect on splanchnic vessels, which reduces splanchnic pressure and decreases blood loss.
Air embolism, a known complication of hepatic resection, can be predicted based on the need for a large hepatectomy (e.g., a right lobectomy) or when the tumor is near the vena cava or involves portal vessels. Low CVP may increase the risk of venous air embolism.