1. Midazolam is the most widely used anxiolytic in children (PO, sublingual, nasal, IV, IM, and rectal routes) that is water soluble, with a rapid onset of action when administered orally and a brief elimination half-life.
2. Dexmedetomidine is an α ₂-agonist sedative whose relative affinity for α ₂:α ₁ receptors is eightfold greater than clonidine. The oral dose, which requires 30 to 60 minutes to provide sedation, is 2.6 to 4 µg/kg.

Pediatric Anesthesia

1. Anatomy and Physiology
2. Pharmacology
3. Respiration
4. Cardiovascular
5. Central Nervous System
6. Renal
7. Hepatic
8. In Vivo Metabolism
9. Intravenous
10. Sedatives
11. Preoperative Assessment
12. Induction of Anesthesia
13. Preoperative Preparation
14. Induction Techniques
15. Maintenance of Anesthesia
16. Emergency and Recovery from Anesthesia
17. Transfer to the Postanesthesia Care Unit (PACU)