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  1. The management of infectious disease is a crucial skill for the intensivist. Epidemiologic studies suggest that more than 70% of adult patients in the intensive care unit (ICU) receive antibiotics and about 50% demonstrate overt signs of infection during their stay. Infection is a major contributor to mortality among the most critically ill, especially following trauma, burns, and extensive surgical insults ( see : Blood Cultures).
  2. Patients who are critically ill have numerous potential sources of infection, as outlined in Table 12.1. Tables 12.2 to 12.4 summarize the common bacterial pathogens referred to herein.
  3. A broad overview of β-lactam antimicrobial spectra is given in Tables 12.5 and 12.6. More detailed treatment recommendations can be found under Section IV.
  4. See regarding how to obtain blood cultures.