REMS
Betapace AF and Sotylize
Absorption: Well absorbed following oral administration (bioavailability 90100%).
Distribution: Crosses the placenta; enters breast milk.
Half-Life: 12 hr (↑ in renal impairment).
Contraindicated in:
Use Cautiously in:
CV: ARRHYTHMIAS, BRADYCARDIA, HF, PULMONARY EDEMA, orthostatic hypotension, peripheral vasoconstriction
Derm: itching, rash
EENT: blurred vision, dry eyes, nasal stuffiness
Endo: hyperglycemia, hypoglycemia
GI: constipation, diarrhea, nausea
GU: erectile dysfunction, ↓libido
MS: arthralgia, back pain, muscle cramps
Neuro: fatigue, weakness, anxiety, dizziness, drowsiness, insomnia, memory loss, mental depression, mental status changes, nervousness, nightmares, paresthesia
Resp: bronchospasm, wheezing
Misc: drug-induced lupus syndrome
Drug-drug:
Ventricular Arrhythmias
Renal Impairment
Atrial Fibrillation/Atrial Flutter
Renal Impairment
Lab Test Considerations:
Toxicity and Overdose:
NDC Code