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Women with breast cancer have a 0.5% per year risk of developing a second breast cancer. Women at increased risk of breast cancer can reduce their risk by 49% by taking tamoxifen or an aromatase inhibitor for 5 years. Women with BRCA-1 mutations can reduce the risk by 90% with simple mastectomy.

For a more detailed discussion, see Lippman ME: Breast Cancer, Chap. 108, p. 523, in HPIM-19.

Outline

Section 6. Hematology and Oncology