Women with breast cancer have a 0.5% per year risk of developing a second breast cancer. Women at increased risk of breast cancer can reduce their risk by 49% by taking tamoxifen or an aromatase inhibitor for 5 years. Women with BRCA-1 mutations can reduce the risk by 90% with simple mastectomy.
For a more detailed discussion, see Lippman ME: Breast Cancer, Chap. 108, p. 523, in HPIM-19. |
Section 6. Hematology and Oncology