Information ⬇
- Howell-Jolly bodies: 1-µm-diameter basophilic cytoplasmic inclusion that represents a residual nuclear fragment, usually single; asplenic pts.
- Basophilic stippling: multiple, punctate basophilic cytoplasmic inclusions composed of precipitated mitochondria and ribosomes; lead poisoning, thalassemia, myelofibrosis.
- Pappenheimer (iron) bodies: iron-containing granules usually composed of mitochondria and ribosomes resemble basophilic stippling but also stain with Prussian blue; lead poisoning, other sideroblastic anemias.
- Heinz bodies: spherical inclusions of precipitated hemoglobin seen only with supravital stains, such as crystal violet; G6PD deficiency (after oxidant stress such as infection, certain drugs), unstable hemoglobin variants.
- Parasites: characteristic intracytoplasmic inclusions; malaria, babesiosis.
Outline ⬆