Therapeutic Classification: antianginals, antihypertensives
Pharmacologic Classification: beta blockers
Absorption: Well absorbed but rapidly undergoes extensive first-pass hepatic metabolism, resulting in 25% bioavailability.
Distribution: Widely distributed to tissues.
Half-Life: 38 hr.
Contraindicated in:
Use Cautiously in:
CV: orthostatic hypotension, ARRHYTHMIAS, BRADYCARDIA, HF
Derm: rash
EENT: blurred vision, dry eyes, intraoperative floppy iris syndrome, nasal stuffiness
Endo: hyperglycemia, hypoglycemia
GI: constipation, diarrhea, nausea
GU: erectile dysfunction, ↓libido
MS: arthralgia, back pain, muscle cramps
Neuro: fatigue, weakness, anxiety, depression, dizziness, drowsiness, insomnia, memory loss, mental status changes, nightmares, paresthesia
Resp: bronchospasm, PULMONARY EDEMA, wheezing
Drug-drug:
Lab Test Considerations:
Toxicity and Overdose:
Before administering IV, have second practitioner independently check original order, dosage calculations, and infusion pump settings.
IV Administration:
NDC Code