section name header

Information

LV hypertrophy, often with asymmetric involvement, especially of the septum or apex; LV contractile function typically excellent with small end-systolic volume. If LV outflow tract obstruction is present, systolic anterior motion (SAM) of mitral valve and midsystolic partial closure of aortic valve are present. Doppler shows early systolic accelerated blood flow through LV outflow tract.

Treatment: Hypertrophic Cardiomyopathy

Strenuous exercise should be avoided. Beta blockers, verapamil, or disopyramide used individually to reduce symptoms. Digoxin, other inotropes, diuretics, and vasodilators are generally contraindicated. Endocarditis antibiotic prophylaxis (Chap. 80. Infective Endocarditis) is necessary only in pts with a prior history of endocarditis. Antiarrhythmic agents, especially amiodarone, may suppress atrial and ventricular arrhythmias. However, consider implantable cardioverter defibrillator for pts with high-risk profile, e.g., history of syncope or aborted cardiac arrest, nonsustained VT, marked LVH (>3 cm), exertional hypotension, or family history of sudden death. In selected pts, LV outflow gradient can be reduced by controlled septal infarction by ethanol injection into the septal artery. Surgical myectomy may be useful in pts refractory to medical therapy.

Outline

Section 8. Cardiology