Disorders of hemostasis can be classified as those that cause a propensity for hemorrhage and those that facilitate inappropriate thrombosis. The disorders are further separated by the involvement in primary hemostasis; the initial platelet plug; or secondary hemostasis, including the clotting cascade and fibrin cross-linkage. Last, hemostatic disorders may reflect inherited genetic disease or acquired deficiencies (Table 16-13: Classification of Inherited Von Willebrand Disease).

1. Disorders of Primary Hemostasis (Table 16-14: Scoring Algorithm for the Diagnosis of Disseminated Intravascular Coagulation)
2. Disorders of Secondary Hemostasis (Table 16-15: Disorders of Secondary Hemostasis)
3. Acquired Disorders of Hemostasis (Table 16-16: Acquired Disorders of Hemostasis)

Hemostasis and Transfusion Medicine

1. Hemostasis and Coagulation
2. Fibrinolysis
3. Laboratory Evaluation of Hemostasis
4. Laboratory Evaluation of Primary Hemostasis
5. Laboratory Evaluation of Secondary Hemostasis and Coagulation
6. Diagnosis of Thromboembolic Disorders
7. Monitoring Anticoagulation Therapeutic Agents
8. Blood Component Production
9. Blood Products and Transfusion Thresholds
10. Physiologic Compensation for Anemia
11. Platelets
12. Fresh Frozen Plasma
13. Cryoprecipitate
14. The Risks of Blood Product Administration
15. Blood Conservation Strategies
16. Disorders of Hemostasis: Diagnosis and Treatment
17. Anticoagulation and Pharmacologic Therapy
18. Prothrombin Complex Concentrates
19. Desmopressin
20. Antifibrinolytic Therapy