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Brief, arrhythmic interruptions of sustained voluntary muscle contraction, usually observed as a brief lapse of posture of wrists in dorsiflexion with arms outstretched, “negative myoclonus.” This “liver flap” may be seen in any encephalopathy related to drug intoxication, organ system failure, or CNS infection. Therapy is correction of the underlying disorder.

For a more detailed discussion, see Olanow CW, Schapira AHV, Obeso JA: Parkinson's Disease and Other Movement Disorders, Chap. 449, p. 2609, in HPIM-19.

Outline

Section 3. Common Patient Presentations