Caffeine is the most common pharmacologic cause of insomnia although a wide range of psychoactive drugs can interfere with sleep, including alcohol and nicotine. Numerous medications, including antidepressants, stimulants, and glucocorticoids, can produce insomnia. Severe rebound insomnia can result from the acute withdrawal of hypnotics, especially following the use of short-acting benzodiazepines.
Section 3. Common Patient Presentations