A. hydrophila causes >85% of Aeromonas infections. Aeromonas organisms proliferate in potable water, freshwater, and soil and are a putative cause of gastroenteritis. Aeromonas causes bacteremia and sepsis in infants and compromised hosts, especially those with cancer, hepatobiliary disease, trauma, or burns. The organisms can produce skin lesions similar to the ecthyma gangrenosum caused by Pseudomonas aeruginosa. Aeromonas causes nosocomial infections related to catheters, surgical incisions, and use of leeches.