Culture of material from a skin lesion or histopathologic examination of a skin biopsy sample can confirm the diagnosis.
Treatment: Sporotrichosis - Cutaneous and lymphocutaneous sporotrichosis is treated with itraconazole (200 mg/d) until 2-4 weeks after lesions resolve, usually for a total of 3-6 months.
- For extracutaneous disease, itraconazole (200 mg bid for ≥12 months) can be given, but initial therapy with liposomal AmB (3-5 mg/kg qd) is more effective for life-threatening pulmonary disease or disseminated infection.
|