Both viral subtypes can cause indistinguishable genital and oral-facial infections. Overall, genital HSV-2 is twice as likely to reactivate as genital HSV-1, and HSV-2 infection recurs 8-10 times more often. In contrast, oral-labial HSV-1 infection recurs more frequently than oral-labial HSV-2 infection. The incubation period for primary infection with either virus is 1-26 days (median, 6-8 days).