Infants typically develop rhinorrhea, low-grade fever, cough, and wheezing; 25-40% of infections result in lower tract disease, including pneumonia, bronchiolitis, and tracheobronchitis.
- In adults, HRSV typically presents as the common cold, but it can cause lower respiratory tract disease with fever, including severe pneumonia in pts who are elderly or immunosuppressed or who have cardiopulmonary disease. HRSV pneumonia has a case-fatality rate of 20-80% among transplant pts.