Approximately 50-70% of infected individuals experience an acute syndrome following primary infection. The acute syndrome follows infection by 3-6 weeks. It can have multiple clinical features (Table 105-1), lasts 1-2 weeks, and resolves spontaneously as an immune response to HIV develops and the viral load diminishes from its peak levels. Most pts will then enter a phase of clinical latency, although an occasional pt will experience rapidly progressive immunologic and clinical deterioration.