Hib vaccine is recommended for all children worldwide; the immunization series should be started at ~2 months of age.

• Secondary attack rates are high among household contacts of pts with Hib disease. All children and adults (except pregnant women) in households with a case of Hib disease and at least one incompletely immunized contact <4 years of age should receive prophylaxis with oral rifampin.
• A vaccine that combines NTHi and pneumococcal antigens is used in many countries outside the United States and has shown partial efficacy in preventing H. influenzae otitis media.